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With Just One Use, Cocaine Can Rewire The Brain

In an alarming new study, researchers found that cocaine may rewire the brain and significantly alter decision-making after just one use.

Time-lapse images show wiring changes (the growth and loss of spines) in the brain cells of a live mouse over multiple days.

In an alarming new study, researchers found that cocaine may rewire the brain and significantly alter decision-making after just one use. The study, performed by UC Berkley and UC San Francisco’s Ernest Gallo Clinic and Research Center, found that “cocaine can speedily rewire high-level brain circuits that support learning, memory and decision-making.” The study also revealed new insight into the role of the brain’s frontal lobe when it comes to drug-seeking behavior. This discovery is important in understanding addiction and its treatment options.

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